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344 The Potential Benefits of Using Senolytics in Colorectal Cancer Treatment

OBJECTIVES/GOALS: Anti-cancer therapies, such as chemotherapy, can induce senescence. Senescent cells may produce factors that can promote tumor progression. In this study, we will investigate the effect of senolytics and anti-cancer treatment on fibroblasts, which are a part of the tumor microenvir...

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Detalles Bibliográficos
Autores principales: Gallegos, Valerie, Rowdo, Florencia Madorsky, White, Jessica, Kuo, Hui-Hsuan, Podaza, Enrique, Martin, Laura, Elemento, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129697/
http://dx.doi.org/10.1017/cts.2023.388