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378 Regulation of renal function by the peroxisome proliferator-activated receptor-alpha: A novel target for treating hypertension

OBJECTIVES/GOALS: Approximately 37 million people in the U.S. have chronic kidney disease, which is a major risk factor for cardiovascular and end stage renal diseases. PPAR-αknockout (KO) mice exhibit increased renal inflammation and blood pressure. In this study, we investigated the role of PPAR-...

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Detalles Bibliográficos
Autores principales: Hatcher, Mark D, Sandberg, Kathryn, Lee, Dexter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129807/
http://dx.doi.org/10.1017/cts.2023.415