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Efficient Generation of Dopaminergic Neurons from Mouse Ventral Midbrain Astrocytes

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by tremors, bradykinesia, and rigidity. PD is caused by loss of dopaminergic (DA) neurons in the midbrain substantia nigra (SN) and therefore, replenishment of DA neurons via stem cell-based therapy is a potential treatmen...

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Detalles Bibliográficos
Autores principales: Han, Jin Yi, Lee, Eun-Hye, Kim, Sang-Mi, Park, Chang-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129851/
https://www.ncbi.nlm.nih.gov/pubmed/36642416
http://dx.doi.org/10.4062/biomolther.2022.140