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Radiation dosimetry and pharmacokinetics of the tau PET tracer florzolotau (18F) in healthy Japanese subjects

OBJECTIVE: Abnormal aggregation of tau in the brain is a major contributing factor in various neurodegenerative diseases. Florzolotau (18F) (florzolotau, APN-1607, PM-PBB3) has been shown to be a probe for tau fibrils in an animal model and patients with Alzheimer’s disease and those with non-Alzhei...

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Detalles Bibliográficos
Autores principales: Miyamoto, Masaomi, Okuyama, Chio, Kagawa, Shinya, Kusano, Kuninori, Takahashi, Masaaki, Takahata, Keisuke, Jang, Ming-Kuei, Yamauchi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129982/
https://www.ncbi.nlm.nih.gov/pubmed/36890399
http://dx.doi.org/10.1007/s12149-023-01828-x