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Natural aging and Alzheimer’s disease pathology increase susceptibility to focused ultrasound-induced blood–brain barrier opening

Focused Ultrasound (FUS) paired with systemically-injected microbubbles (μB) is capable of transiently opening the blood–brain barrier (BBBO) for noninvasive and targeted drug delivery to the brain. FUS-BBBO is also capable of modulating the neuroimmune system, further qualifying its therapeutic pot...

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Detalles Bibliográficos
Autores principales: Noel, R. L., Batts, A. J., Ji, R., Pouliopoulos, A. N., Bae, S., Kline-Schoder, A. R., Konofagou, E. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130033/
https://www.ncbi.nlm.nih.gov/pubmed/37185578
http://dx.doi.org/10.1038/s41598-023-30466-6