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Neuropathological signatures revealed by transcriptomic and proteomic analysis in Pten-deficient mouse models

PTEN hamartoma tumour syndrome is characterised by mutations in the human PTEN gene. We performed transcriptomic and proteomic analyses of neural tissues and primary cultures from heterozygous and homozygous Pten-knockout mice. The somatosensory cortex of heterozygous Pten-knockout mice was enriched...

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Detalles Bibliográficos
Autores principales:	Cheung, Stanley K. K., Kwok, Jacinda, Or, Penelope M. Y., Wong, Chi Wai, Feng, Bo, Choy, Kwong Wai, Chang, Raymond C. C., Burbach, J. Peter H., Cheng, Alfred S. L., Chan, Andrew M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130134/ https://www.ncbi.nlm.nih.gov/pubmed/37185447 http://dx.doi.org/10.1038/s41598-023-33869-7

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