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PI3Kα Translocation Mediates Nuclear PtdIns(3,4,5)P(3) Effector Signaling in Colorectal Cancer

The canonical view of PI3Kα signaling describes phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) generation and activation of downstream effectors at the plasma membrane or at microtubule-bound endosomes. Here, we show that colorectal cancer (CRC) cell lines exhibit a diverse plasma memb...

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Detalles Bibliográficos
Autores principales:	Palmieri, Michelle, Catimel, Bruno, Mouradov, Dmitri, Sakthianandeswaren, Anuratha, Kapp, Eugene, Ang, Ching-Seng, Williamson, Nicholas A., Nowell, Cameron J., Christie, Michael, Desai, Jayesh, Gibbs, Peter, Burgess, Antony W., Sieber, Oliver M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130476/ https://www.ncbi.nlm.nih.gov/pubmed/36931626 http://dx.doi.org/10.1016/j.mcpro.2023.100529

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