Glucagon Acting at the GLP-1 Receptor Contributes to β-Cell Regeneration Induced by Glucagon Receptor Antagonism in Diabetic Mice

Dysfunction of glucagon-secreting α-cells participates in the progression of diabetes, and glucagon receptor (GCGR) antagonism is regarded as a novel strategy for diabetes therapy. GCGR antagonism upregulates glucagon and glucagon-like peptide 1 (GLP-1) secretion and, notably, promotes β-cell regene...

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Detalles Bibliográficos
Autores principales: Wei, Tianjiao, Cui, Xiaona, Jiang, Yafei, Wang, Kangli, Wang, Dandan, Li, Fei, Lin, Xiafang, Gu, Liangbiao, Yang, Kun, Yang, Jin, Hong, Tianpei, Wei, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130488/
https://www.ncbi.nlm.nih.gov/pubmed/36826938
http://dx.doi.org/10.2337/db22-0784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130488/
https://www.ncbi.nlm.nih.gov/pubmed/36826938
http://dx.doi.org/10.2337/db22-0784

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