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RAGE and its ligand amyloid beta promote retinal ganglion cell loss following ischemia-reperfusion injury
INTRODUCTION: Glaucoma is a progressive neurodegenerative disease associated with age. Accumulation of amyloid-beta (Aß) proteins in the ganglion cell layer (GCL) and subsequent retinal ganglion cell (RGC) loss is an established pathological hallmark of the disease. The mechanism through which Aß pr...
Autores principales: | Seyed Hosseini Fin, Nafiseh, Georgevsky, Dana, Sukkar, Maria B., Golzan, S. Mojtaba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130520/ https://www.ncbi.nlm.nih.gov/pubmed/37124398 http://dx.doi.org/10.3389/fncel.2023.1156084 |
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