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RAGE and its ligand amyloid beta promote retinal ganglion cell loss following ischemia-reperfusion injury

INTRODUCTION: Glaucoma is a progressive neurodegenerative disease associated with age. Accumulation of amyloid-beta (Aß) proteins in the ganglion cell layer (GCL) and subsequent retinal ganglion cell (RGC) loss is an established pathological hallmark of the disease. The mechanism through which Aß pr...

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Detalles Bibliográficos
Autores principales: Seyed Hosseini Fin, Nafiseh, Georgevsky, Dana, Sukkar, Maria B., Golzan, S. Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130520/
https://www.ncbi.nlm.nih.gov/pubmed/37124398
http://dx.doi.org/10.3389/fncel.2023.1156084

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