Dual targeting of aberrant DNA and histone methylation synergistically suppresses tumor cell growth in ATL

Adult T-cell leukemia/lymphoma (ATL) is a malignancy of mature CD4(+) T cells caused by human T-cell lymphotropic virus type 1 (HTLV-1)–induced T-cell transformation. After infection with HTLV-1, it takes several decades for HTLV-1 carriers to develop ATL. The prognosis of ATL remains poor despite s...

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Detalles Bibliográficos
Autores principales: Kurahashi, Yuki, Watanabe, Tatsuro, Yamamoto, Yuta, Ureshino, Hiroshi, Kamachi, Kazuharu, Yoshida-Sakai, Nao, Fukuda-Kurahashi, Yuki, Yamashita, Satoshi, Hattori, Naoko, Nakamura, Hideaki, Kawaguchi, Atsushi, Ushijima, Toshikazu, Sueoka, Eisaburo, Kimura, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130614/
https://www.ncbi.nlm.nih.gov/pubmed/36516085
http://dx.doi.org/10.1182/bloodadvances.2022008362

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