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The RAS-24: Development and validation of an adherence-to-medication scale for severe mental illness patients
INTRODUCTION: Several studies have found that most patients with severe mental illness (SMI) and comorbid (physical) conditions are partially or wholly nonadherent to their medication regimens. Nonadherence to treatment is a serious concern, affecting the successful management of patients with SMIs....
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cambridge University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130847/ https://www.ncbi.nlm.nih.gov/pubmed/37125053 http://dx.doi.org/10.1017/cts.2023.527 |
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author | Ralat, Sandra I. Rodríguez-Gómez, José |
author_facet | Ralat, Sandra I. Rodríguez-Gómez, José |
author_sort | Ralat, Sandra I. |
collection | PubMed |
description | INTRODUCTION: Several studies have found that most patients with severe mental illness (SMI) and comorbid (physical) conditions are partially or wholly nonadherent to their medication regimens. Nonadherence to treatment is a serious concern, affecting the successful management of patients with SMIs. Psychiatric disorders tend to worsen and persist in nonadherent patients, worsening their overall health. The study described herein aimed to develop and validate a scale (the Ralat Adherence Scale) to measure nonadherence behaviors in a culturally sensitive way. MATERIALS AND METHODS: Guided by a previous study that explored the primary reasons for nonadherence in Puerto Rican patients, we developed a pool of 147 items linked to the concept of adherence. Nine experts reviewed the meaning, content, clarity, and relevance of the individual items, and a content validity ratio was calculated for each one. Forty items remained in the scale’s first version. This version was administered to 160 patients (21–60 years old). All the participants had a diagnosis of bipolar disorder, major depressive disorder, or schizoaffective disorder. The STROBE checklist was used as the reporting guideline. RESULTS: The scale had very good internal consistency (Cronbach’s alpha = 0.812). After a factor analysis, the scale was reduced to 24 items; the new scale had a Cronbach’s alpha of 0.900. CONCLUSIONS: This adherence scale is a self-administered instrument with very good psychometric properties; it has yielded important information about nonadherence behaviors. The scale can help health professionals and researchers to assess patient adherence or nonadherence to a medication regimen. |
format | Online Article Text |
id | pubmed-10130847 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-101308472023-04-27 The RAS-24: Development and validation of an adherence-to-medication scale for severe mental illness patients Ralat, Sandra I. Rodríguez-Gómez, José J Clin Transl Sci Research Article INTRODUCTION: Several studies have found that most patients with severe mental illness (SMI) and comorbid (physical) conditions are partially or wholly nonadherent to their medication regimens. Nonadherence to treatment is a serious concern, affecting the successful management of patients with SMIs. Psychiatric disorders tend to worsen and persist in nonadherent patients, worsening their overall health. The study described herein aimed to develop and validate a scale (the Ralat Adherence Scale) to measure nonadherence behaviors in a culturally sensitive way. MATERIALS AND METHODS: Guided by a previous study that explored the primary reasons for nonadherence in Puerto Rican patients, we developed a pool of 147 items linked to the concept of adherence. Nine experts reviewed the meaning, content, clarity, and relevance of the individual items, and a content validity ratio was calculated for each one. Forty items remained in the scale’s first version. This version was administered to 160 patients (21–60 years old). All the participants had a diagnosis of bipolar disorder, major depressive disorder, or schizoaffective disorder. The STROBE checklist was used as the reporting guideline. RESULTS: The scale had very good internal consistency (Cronbach’s alpha = 0.812). After a factor analysis, the scale was reduced to 24 items; the new scale had a Cronbach’s alpha of 0.900. CONCLUSIONS: This adherence scale is a self-administered instrument with very good psychometric properties; it has yielded important information about nonadherence behaviors. The scale can help health professionals and researchers to assess patient adherence or nonadherence to a medication regimen. Cambridge University Press 2023-04-18 /pmc/articles/PMC10130847/ /pubmed/37125053 http://dx.doi.org/10.1017/cts.2023.527 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided that no alterations are made and the original article is properly cited. The written permission of Cambridge University Press must be obtained prior to any commercial use and/or adaptation of the article. |
spellingShingle | Research Article Ralat, Sandra I. Rodríguez-Gómez, José The RAS-24: Development and validation of an adherence-to-medication scale for severe mental illness patients |
title | The RAS-24: Development and validation of an adherence-to-medication scale for severe mental illness patients |
title_full | The RAS-24: Development and validation of an adherence-to-medication scale for severe mental illness patients |
title_fullStr | The RAS-24: Development and validation of an adherence-to-medication scale for severe mental illness patients |
title_full_unstemmed | The RAS-24: Development and validation of an adherence-to-medication scale for severe mental illness patients |
title_short | The RAS-24: Development and validation of an adherence-to-medication scale for severe mental illness patients |
title_sort | ras-24: development and validation of an adherence-to-medication scale for severe mental illness patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130847/ https://www.ncbi.nlm.nih.gov/pubmed/37125053 http://dx.doi.org/10.1017/cts.2023.527 |
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