Cargando…

Scar formation in the presence of mitomycin C and the anti-fibrotic antibody in a rabbit model of glaucoma microsurgery: A pilot study

PURPOSE: This study aimed to evaluate the utility of a rationally engineered antibody that directly blocks collagen fibrillogenesis to reduce scar tissue formation associated with subconjunctival glaucoma surgery. MATERIAL AND METHODS: Fourteen eyes of 7 adult rabbits underwent glaucoma filtering su...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shukla, Aakriti Garg, Milman, Tatyana, Fertala, Jolanta, Steplewski, Andrzej, Fertala, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130883/ https://www.ncbi.nlm.nih.gov/pubmed/37123929 http://dx.doi.org/10.1016/j.heliyon.2023.e15368

Ejemplares similares

Corneal Wound Healing in the Presence of Antifibrotic Antibody Targeting Collagen Fibrillogenesis: A Pilot Study
por: Syed, Zeba A., et al.
Publicado: (2023)

Collagen‐rich deposit formation in the sciatic nerve after injury and surgical repair: A study of collagen‐producing cells in a rabbit model
por: Fertala, Jolanta, et al.
Publicado: (2020)

Patterns of production of collagen‐rich deposits in peripheral nerves in response to injury: A pilot study in a rabbit model
por: Rivlin, Michael, et al.
Publicado: (2017)

The impact of cholesterol deposits on the fibrillar architecture of the Achilles tendon in a rabbit model of hypercholesterolemia
por: Steplewski, Andrzej, et al.
Publicado: (2019)

Prospects and limitations of improving skeletal growth in a mouse model of spondyloepiphyseal dysplasia caused by R992C (p.R1192C) substitution in collagen II
por: Arita, Machiko, et al.
Publicado: (2017)

Inhibition of collagen fibril formation
por: Steplewski, Andrzej, et al.
Publicado: (2012)

Mechanisms of reducing joint stiffness by blocking collagen fibrillogenesis in a rabbit model of posttraumatic arthrofibrosis
por: Steplewski, Andrzej, et al.
Publicado: (2021)

Extracellular Targets to Reduce Excessive Scarring in Response to Tissue Injury
por: Fertala, Jolanta, et al.
Publicado: (2023)

Three Decades of Research on Recombinant Collagens: Reinventing the Wheel or Developing New Biomedical Products?
por: Fertala, Andrzej
Publicado: (2020)

Profibrotic behavior of fibroblasts derived from patients that develop posttraumatic shoulder stiffness
por: Hendy, Benjamin A., et al.
Publicado: (2023)

Gingival Fibromatosis with Significant De Novo Formation of Fibrotic Tissue and a High Rate of Recurrence
por: Gawron, Katarzyna, et al.
Publicado: (2016)

Functional and structural studies of tolloid-like 1 mutants associated with atrial-septal defect 6
por: Sieron, Lukasz, et al.
Publicado: (2019)

Collagen Structure-Function Mapping Informs Applications for Regenerative Medicine
por: San Antonio, James D., et al.
Publicado: (2020)

Fibrotic Scar in Neurodegenerative Diseases
por: D'Ambrosi, Nadia, et al.
Publicado: (2020)

Developmental Upregulation of an Alternative Form of pcp2 with Reduced GDI Activity
por: Barski, Jaroslaw J., et al.
Publicado: (2013)

Outcomes of Trabeculectomy With and Without Mitomycin C in Pseudoexfoliative Glaucoma Compared With Mitomycin C in Primary Open Angle Glaucoma
por: LOPES, Ana Sofia, et al.
Publicado: (2019)

Fibrotic Scar in CNS Injuries: From the Cellular Origins of Fibroblasts to the Molecular Processes of Fibrotic Scar Formation
por: Ayazi, Maryam, et al.
Publicado: (2022)

Bleb morphology and histology in a rabbit model of glaucoma filtration surgery using Ozurdex(®) or mitomycin-C
por: SooHoo, Jeffrey R., et al.
Publicado: (2012)

Anti-fibrotic effect of adipose-derived stem cells on fibrotic scars
por: Vanderstichele, Sophie, et al.
Publicado: (2022)

Neuroprotection in glaucoma
por: Vishwaraj, C R, et al.
Publicado: (2022)

Effects of Valproic Acid and Mitomycin C Combination Therapy in a Rabbit Model of Minimally Invasive Glaucoma Surgery
por: Seet, Li-Fong, et al.
Publicado: (2022)

In Vitro Study of Combined Application of Bevacizumab and 5-Fluorouracil or Bevacizumab and Mitomycin C to Inhibit Scar Formation in Glaucoma Filtration Surgery
por: Zhang, Yuanyuan, et al.
Publicado: (2019)

The Effect of Dry Eye Disease on Scar Formation in Rabbit Glaucoma Filtration Surgery
por: Ji, Hong, et al.
Publicado: (2017)

Mitomycin-C Needle Bleb Revision in Congenital Glaucoma
por: Elsayed, Thanaa Helmy Mohamed, et al.
Publicado: (2010)

ALK5 Inhibition of Subconjunctival Scarring From Glaucoma Surgery: Effects of SB-431542 Compared to Mitomycin C in Human Tenon's Capsule Fibroblasts
por: Teplitsky, Jack E., et al.
Publicado: (2023)

Can trainees perform Ahmed glaucoma valve surgery as effectively as attendings?
por: Ustaoglu, Melih, et al.
Publicado: (2022)

A review of the efficacy of mitomycin C in glaucoma filtration surgery
por: Al Habash, Ahmed, et al.
Publicado: (2015)

Is canaloplasty with mitomycin c a safe procedure in myopic glaucoma?
por: Dooling, Vivienne, et al.
Publicado: (2022)

Effect of Novel Design Modifications on Fibrotic Encapsulation: An In Vivo Glaucoma Drainage Device Study in a Rabbit Model
por: Fischer, Nathan A., et al.
Publicado: (2020)

Comparison of Surgical Outcomes between Trabeculectomy with Mitomycin C and Ahmed Valve Implantation with Mitomycin C in Eyes with Uveitic Glaucoma
por: Lee, Seung Yeop, et al.
Publicado: (2022)

In vitro analyses of the anti-fibrotic effect of SPARC silencing in human Tenon’s fibroblasts: comparisons with mitomycin C
por: Seet, Li-Fong, et al.
Publicado: (2012)

The Role of Epigenetics in the Fibrotic Processes Associated with Glaucoma
por: McDonnell, Fiona, et al.
Publicado: (2014)

Intravitreal bevacizumab with or without mitomycin C trabeculectomy in the treatment of neovascular glaucoma
por: Marey, Hatem M, et al.
Publicado: (2011)

The Influence of Phacoemulsification on Surgical Outcomes of Trabeculectomy with Mitomycin-C for Uveitic Glaucoma
por: Nishizawa, Asaho, et al.
Publicado: (2016)

Simultaneous use of amniotic membrane and Mitomycin C in trabeculectomy for primary glaucoma
por: Yadava, Usha, et al.
Publicado: (2017)

Effects of topical mitomycin-C on the tracheal epithelia of rabbits following tracheostomy
por: ÇALIK, Saniye Göknil, et al.
Publicado: (2021)

Cyclosporine A-loaded drug delivery systems inhibit scar formation after glaucoma surgery in rabbits
por: Dai, Zhao-Xing, et al.
Publicado: (2019)

Midterm outcome of mitomycin C augmented trabeculectomy in open angle glaucoma versus angle closure glaucoma
por: Maheshwari, Devendra, et al.
Publicado: (2019)

Fibrotic scar after experimental autoimmune encephalomyelitis inhibits oligodendrocyte differentiation
por: Yahn, Stephanie L., et al.
Publicado: (2019)

Microsurgery
Publicado: (1979)

Cannot write session to /tmp/vufind_sessions/sess_md8m9om5k9ldjne4se3j054qj3