Transition-metal-catalyzed C–H bond activation as a sustainable strategy for the synthesis of fluorinated molecules: an overview

The last decade has witnessed the emergence of innovative synthetic tools for the synthesis of fluorinated molecules. Among these approaches, the transition-metal-catalyzed functionalization of various scaffolds with a panel of fluorinated groups (XR(F), X = S, Se, O) offered straightforward access...

Descripción completa

Detalles Bibliográficos
Autores principales: Monsigny, Louis, Doche, Floriane, Besset, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130906/
https://www.ncbi.nlm.nih.gov/pubmed/37123090
http://dx.doi.org/10.3762/bjoc.19.35
_version_ 1785031061265186816
author Monsigny, Louis
Doche, Floriane
Besset, Tatiana
author_facet Monsigny, Louis
Doche, Floriane
Besset, Tatiana
author_sort Monsigny, Louis
collection PubMed
description The last decade has witnessed the emergence of innovative synthetic tools for the synthesis of fluorinated molecules. Among these approaches, the transition-metal-catalyzed functionalization of various scaffolds with a panel of fluorinated groups (XR(F), X = S, Se, O) offered straightforward access to high value-added compounds. This review will highlight the main advances made in the field with the transition-metal-catalyzed functionalization of C(sp(2)) and C(sp(3)) centers with SCF(3), SeCF(3), or OCH(2)CF(3) groups among others, by C–H bond activation. The scope and limitations of these transformations are discussed in this review.
format Online
Article
Text
id pubmed-10130906
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-101309062023-04-27 Transition-metal-catalyzed C–H bond activation as a sustainable strategy for the synthesis of fluorinated molecules: an overview Monsigny, Louis Doche, Floriane Besset, Tatiana Beilstein J Org Chem Review The last decade has witnessed the emergence of innovative synthetic tools for the synthesis of fluorinated molecules. Among these approaches, the transition-metal-catalyzed functionalization of various scaffolds with a panel of fluorinated groups (XR(F), X = S, Se, O) offered straightforward access to high value-added compounds. This review will highlight the main advances made in the field with the transition-metal-catalyzed functionalization of C(sp(2)) and C(sp(3)) centers with SCF(3), SeCF(3), or OCH(2)CF(3) groups among others, by C–H bond activation. The scope and limitations of these transformations are discussed in this review. Beilstein-Institut 2023-04-17 /pmc/articles/PMC10130906/ /pubmed/37123090 http://dx.doi.org/10.3762/bjoc.19.35 Text en Copyright © 2023, Monsigny et al. https://creativecommons.org/licenses/by/4.0/This is an open access article licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-journals.org/bjoc/terms/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this article could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material.
spellingShingle Review
Monsigny, Louis
Doche, Floriane
Besset, Tatiana
Transition-metal-catalyzed C–H bond activation as a sustainable strategy for the synthesis of fluorinated molecules: an overview
title Transition-metal-catalyzed C–H bond activation as a sustainable strategy for the synthesis of fluorinated molecules: an overview
title_full Transition-metal-catalyzed C–H bond activation as a sustainable strategy for the synthesis of fluorinated molecules: an overview
title_fullStr Transition-metal-catalyzed C–H bond activation as a sustainable strategy for the synthesis of fluorinated molecules: an overview
title_full_unstemmed Transition-metal-catalyzed C–H bond activation as a sustainable strategy for the synthesis of fluorinated molecules: an overview
title_short Transition-metal-catalyzed C–H bond activation as a sustainable strategy for the synthesis of fluorinated molecules: an overview
title_sort transition-metal-catalyzed c–h bond activation as a sustainable strategy for the synthesis of fluorinated molecules: an overview
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130906/
https://www.ncbi.nlm.nih.gov/pubmed/37123090
http://dx.doi.org/10.3762/bjoc.19.35
work_keys_str_mv AT monsignylouis transitionmetalcatalyzedchbondactivationasasustainablestrategyforthesynthesisoffluorinatedmoleculesanoverview
AT dochefloriane transitionmetalcatalyzedchbondactivationasasustainablestrategyforthesynthesisoffluorinatedmoleculesanoverview
AT bessettatiana transitionmetalcatalyzedchbondactivationasasustainablestrategyforthesynthesisoffluorinatedmoleculesanoverview

Ejemplares similares