Cargando…
Identification and characterization of the CDK1-BMAL1-UHRF1 pathway driving tumor progression
The abnormal regulation of BMAL1 could lead to the occurrence and progression of various tumors. However, the mechanism of phosphorylation regulation of BMAL1 in tumorigenesis remains poorly understood. In this study, we report a previously unrecognized BMAL1 dephosphorylation pathway that promotes...
Autores principales: | Wang, Dan, Wang, Fenglin, Wang, Shengfeng, Chu, Ling, Tang, Daolin, Chen, Pan, Yang, Minghua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130925/ https://www.ncbi.nlm.nih.gov/pubmed/37123229 http://dx.doi.org/10.1016/j.isci.2023.106544 |
Ejemplares similares
-
Circadian clock protein Bmal1 accelerates acute myeloid leukemia by inhibiting ferroptosis through the EBF3/ALOX15 axis
por: Wang, Dan, et al.
Publicado: (2023) -
SHMT2 Drives the Progression of Colorectal Cancer by Regulating UHRF1 Expression
por: Cui, Ximao, et al.
Publicado: (2022) -
Crosstalk between macrophage-derived PGE(2) and tumor UHRF1 drives hepatocellular carcinoma progression
por: Zhang, Jian, et al.
Publicado: (2022) -
Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression
por: Benavente, Claudia A., et al.
Publicado: (2014) -
Upregulation of UHRF1 promotes the progression of melanoma by inducing cell proliferation
por: Wei, Chuanyuan, et al.
Publicado: (2018)