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The circadian clock remains intact, but with dampened hormonal output in heart failure
BACKGROUND: Circadian (24-h) rhythms are important regulators in physiology and disease, but systemic disease may disrupt circadian rhythmicity. Heart failure (HF) is a systemic disease affecting hormonal regulation. We investigate whether HF affects the rhythmic expression of melatonin and cortisol...
Autores principales: | Crnko, Sandra, Printezi, Markella I., Zwetsloot, Peter-Paul M., Leiteris, Laurynas, Lumley, Andrew I., Zhang, Lu, Ernens, Isabelle, Jansen, Tijn P.J., Homsma, Lilian, Feyen, Dries, van Faassen, Martijn, du Pré, Bastiaan C., Gaillard, Carlo A.J.M., Kemperman, Hans, Oerlemans, Marish I.F.J., Doevendans, Pieter A.F.M., May, Anne M., Zuithoff, Nicolaas P.A., Sluijter, Joost P.G., Devaux, Yvan, van Laake, Linda W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131037/ https://www.ncbi.nlm.nih.gov/pubmed/37075492 http://dx.doi.org/10.1016/j.ebiom.2023.104556 |
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