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Data-driven determination of number of discrete conformations in single-particle cryo-EM

BACKGROUND AND OBJECTIVE: One of the strengths of single-particle cryo-EM compared to other structural determination techniques is its ability to image heterogeneous samples containing multiple molecular species, different oligomeric states or distinct conformations. This is achieved using routines...

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Detalles Bibliográficos
Autores principales: Zhou, Ye, Moscovich, Amit, Bartesaghi, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131080/
https://www.ncbi.nlm.nih.gov/pubmed/35597206
http://dx.doi.org/10.1016/j.cmpb.2022.106892

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