Therapeutic targeting of CNBP phase separation inhibits ribosome biogenesis and neuroblastoma progression via modulating SWI/SNF complex activity

BACKGROUND: Neuroblastoma (NB) is the most common extracranial malignancy in childhood; however, the mechanisms underlying its aggressive characteristics still remain elusive. METHODS: Integrative data analysis was performed to reveal tumour‐driving transcriptional regulators. Co‐immunoprecipitation...

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Detalles Bibliográficos
Autores principales: Hu, Anpei, Chen, Guo, Bao, Banghe, Guo, Yanhua, Li, Dan, Wang, Xiaojing, Wang, Jianqun, Li, Qilan, Zhou, Yi, Gao, Haiyang, Song, Jiyu, Du, Xinyi, Zheng, Liduan, Tong, Qiangsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131295/
https://www.ncbi.nlm.nih.gov/pubmed/37186134
http://dx.doi.org/10.1002/ctm2.1235

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