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MicroRNA-19b-3p dysfunction of mesenchymal stem cell-derived exosomes from patients with abdominal aortic aneurysm impairs therapeutic efficacy

Senescence of vascular smooth muscle cells (VSMCs) contributes to the formation of abdominal aortic aneurysm (AAA). Although mesenchymal stem cell exosomes (MSC-EXO) have been confirmed to restrict the development of AAA, their biological activity depends largely on the physiological state of the MS...

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Detalles Bibliográficos
Autores principales: Zhang, Yuxiao, Huang, Xiaoran, Sun, Tucheng, Shi, Linli, Liu, Baojuan, Hong, Yimei, Fu, Qing-Ling, Zhang, Yuelin, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131394/
https://www.ncbi.nlm.nih.gov/pubmed/37101174
http://dx.doi.org/10.1186/s12951-023-01894-3