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MicroRNA-19b-3p dysfunction of mesenchymal stem cell-derived exosomes from patients with abdominal aortic aneurysm impairs therapeutic efficacy
Senescence of vascular smooth muscle cells (VSMCs) contributes to the formation of abdominal aortic aneurysm (AAA). Although mesenchymal stem cell exosomes (MSC-EXO) have been confirmed to restrict the development of AAA, their biological activity depends largely on the physiological state of the MS...
Autores principales: | Zhang, Yuxiao, Huang, Xiaoran, Sun, Tucheng, Shi, Linli, Liu, Baojuan, Hong, Yimei, Fu, Qing-Ling, Zhang, Yuelin, Li, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131394/ https://www.ncbi.nlm.nih.gov/pubmed/37101174 http://dx.doi.org/10.1186/s12951-023-01894-3 |
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