Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal‐derived extracellular vesicles

INTRODUCTION: Intellectual disability, accelerated aging, and early‐onset Alzheimer‐like neurodegeneration are key brain pathological features of Down syndrome (DS). Although growing research aims at the identification of molecular pathways underlying the aging trajectory of DS population, data on i...

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Detalles Bibliográficos
Autores principales: Perluigi, Marzia, Picca, Anna, Montanari, Elita, Calvani, Riccardo, Marini, Federico, Matassa, Roberto, Tramutola, Antonella, Villani, Alberto, Familiari, Giuseppe, Domenico, Fabio Di, Butterfield, D. Allan, Oh, Kenneth J., Marzetti, Emanuele, Valentini, Diletta, Barone, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131479/
https://www.ncbi.nlm.nih.gov/pubmed/34812584
http://dx.doi.org/10.1002/alz.12499

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