Single-cell transcriptomes reveal heterogeneity of chlorine-induced mice acute lung injury and the inhibitory effect of pentoxifylline on ferroptosis

To investigate the effect of pentoxifylline (PTX) on Chlorine (Cl(2))-induced acute lung injury (ALI) by single-cell RNA sequencing (scRNA-seq). Female BALB/c mice were exposed to Cl(2) at 400 ppm for 15 min. H&E staining was used to observe the degree of lung injury. scRNA-seq was conducted to...

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Detalles Bibliográficos
Autores principales: Zhao, Chen-qian, Wang, Chong, Liu, Meng-meng, Cao, Meng, Peng, Jie, Kong, De-qin, Ren, Xiao-ting, Liu, Rui, Hai, Chun-xu, Zhang, Xiao-di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131515/
https://www.ncbi.nlm.nih.gov/pubmed/37100790
http://dx.doi.org/10.1038/s41598-023-32093-7

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