De novo design of protein interactions with learned surface fingerprints

Physical interactions between proteins are essential for most biological processes governing life(1). However, the molecular determinants of such interactions have been challenging to understand, even as genomic, proteomic and structural data increase. This knowledge gap has been a major obstacle fo...

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Detalles Bibliográficos
Autores principales: Gainza, Pablo, Wehrle, Sarah, Van Hall-Beauvais, Alexandra, Marchand, Anthony, Scheck, Andreas, Harteveld, Zander, Buckley, Stephen, Ni, Dongchun, Tan, Shuguang, Sverrisson, Freyr, Goverde, Casper, Turelli, Priscilla, Raclot, Charlène, Teslenko, Alexandra, Pacesa, Martin, Rosset, Stéphane, Georgeon, Sandrine, Marsden, Jane, Petruzzella, Aaron, Liu, Kefang, Xu, Zepeng, Chai, Yan, Han, Pu, Gao, George F., Oricchio, Elisa, Fierz, Beat, Trono, Didier, Stahlberg, Henning, Bronstein, Michael, Correia, Bruno E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131520/
https://www.ncbi.nlm.nih.gov/pubmed/37100904
http://dx.doi.org/10.1038/s41586-023-05993-x

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