Phase-separated nucleocapsid protein of SARS-CoV-2 suppresses cGAS-DNA recognition by disrupting cGAS-G3BP1 complex

Currently, the incidence and fatality rate of SARS-CoV-2 remain continually high worldwide. COVID-19 patients infected with SARS-CoV-2 exhibited decreased type I interferon (IFN-I) signal, along with limited activation of antiviral immune responses as well as enhanced viral infectivity. Dramatic pro...

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Detalles Bibliográficos
Autores principales: Cai, Sihui, Zhang, Chenqiu, Zhuang, Zhen, Zhang, Shengnan, Ma, Ling, Yang, Shuai, Zhou, Tao, Wang, Zheyu, Xie, Weihong, Jin, Shouheng, Zhao, Jincun, Guan, Xiangdong, Wu, Jianfeng, Cui, Jun, Wu, Yaoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131525/
https://www.ncbi.nlm.nih.gov/pubmed/37100798
http://dx.doi.org/10.1038/s41392-023-01420-9

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