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Experimental and Theoretical Investigation of Inclusion Complexes of β-Cyclodextrin with Fingolimod

The solubilizing effect of β-cyclodextrin on fingolimod, a new generation immunosuppressant, is studied for the first time. A possible 20× increase in the solubility of fingolimod due to the penetration of the hydrophobic fragment of the drug molecule into the macrocyclic cavity of the cyclodextrin...

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Detalles Bibliográficos
Autores principales:	Garibyan, A. A., Delyagina, E. S., Antipova, M. L., Odintsova, E. G., Petrenko, V. E., Terekhova, I. V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pleiades Publishing 2023
Materias:	Physical Chemistry of Solutions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131540/ http://dx.doi.org/10.1134/S0036024423030135

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