Cargando…

A Multicomponent Intervention to Train and Support Family Medicine Providers to Promote Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in the Deep South: Protocol for the PrEP-Pro Study

BACKGROUND: Pre-exposure prophylaxis (PrEP) is a highly effective biomedical prevention intervention and a major strategy for reducing the HIV burden in the United States. However, PrEP provision and uptake remain lower than estimated needs, and in ways that may exacerbate HIV disparities among Blac...

Descripción completa

Detalles Bibliográficos
Autores principales: Isehunwa, Oluwaseyi O, Hill, Samantha V, Menninger, Alex Tobias, Hubner, Brook, Krakower, Douglas, Long, Dustin M, Pratt, Madeline C, Clement, Meredith E, Wagoner, Nicholas Van, Lanzi, Robin Gaines, Simpson, Tina, Elopre, Latesha, Matthews, Lynn T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131664/
https://www.ncbi.nlm.nih.gov/pubmed/36943364
http://dx.doi.org/10.2196/44908
_version_ 1785031224762302464
author Isehunwa, Oluwaseyi O
Hill, Samantha V
Menninger, Alex Tobias
Hubner, Brook
Krakower, Douglas
Long, Dustin M
Pratt, Madeline C
Clement, Meredith E
Wagoner, Nicholas Van
Lanzi, Robin Gaines
Simpson, Tina
Elopre, Latesha
Matthews, Lynn T
author_facet Isehunwa, Oluwaseyi O
Hill, Samantha V
Menninger, Alex Tobias
Hubner, Brook
Krakower, Douglas
Long, Dustin M
Pratt, Madeline C
Clement, Meredith E
Wagoner, Nicholas Van
Lanzi, Robin Gaines
Simpson, Tina
Elopre, Latesha
Matthews, Lynn T
author_sort Isehunwa, Oluwaseyi O
collection PubMed
description BACKGROUND: Pre-exposure prophylaxis (PrEP) is a highly effective biomedical prevention intervention and a major strategy for reducing the HIV burden in the United States. However, PrEP provision and uptake remain lower than estimated needs, and in ways that may exacerbate HIV disparities among Black adolescent girls and young women in the southern United States. Data suggest that gaps in provider knowledge of HIV epidemiology and PrEP and skills assessing sexual health practices are important barriers to provision and uptake, with limited evidence-based interventions to address these gaps. OBJECTIVE: This paper describes the “PrEP-Pro” intervention, a multicomponent intervention to train and support family medicine (FM) trainees to promote PrEP for adolescent girls and young women in Alabama. METHODS: The PrEP-Pro intervention comprises 3 main components guided by the Capability-Opportunity-Motivation-Behavior (COM-B) model for behavioral change and the Consolidated Framework for Implementation Research (CFIR): (1) provider HIV epidemiology and PrEP education, (2) sexual history taking, and (3) PrEP Champions. In phase 1, we will work with community advisory boards (providers and clients) and then conduct focus groups with FM trainees to adapt content to train FM residents on HIV epidemiology and PrEP and develop implementation strategies, including provider-facing tools and client-facing educational materials. In phase 2, we will pretest and then pilot-test the initially adapted PrEP-Pro intervention with FM trainees. FM trainees will complete baseline, 3-, and 6-month questionnaires post PrEP-Pro intervention. We will also conduct in-depth interviews (IDIs) with FM pilot participants, adolescent girls and young women who accessed care after the PrEP-Pro pilot, and key stakeholders. The primary outcomes are PrEP-Pro acceptability and feasibility, which would be assessed using validated instruments at months 3 (among pretest participants) and 6 (among pilot participants). Secondary outcomes will also be assessed, including PrEP knowledge, sexual history-taking attitudes and practices, PrEP prescriptions among adolescent girls and young women encounters, and sexually transmitted infections (STIs) and HIV testing among adolescent girls and young women encounters in 6 months. RESULTS: Study results will be disseminated to practices, state health officials, and other key stakeholders to solicit feedback on implementation opportunities and challenges to inform a hybrid effectiveness implementation trial. Our results will also be presented at local and national conferences and submitted to peer-reviewed journals. CONCLUSIONS: As PrEP grows, there is a pressing need to train FM providers and develop appropriate, contextually relevant tools to support PrEP implementation. The PrEP-Pro intervention is a multicomponent intervention to train FM residents across Alabama on sexual history-taking, PrEP provision for adolescent girls and young women, and supporting practice-based PrEP Champions. The PrEP-Pro intervention is anticipated to increase PrEP prescriptions for adolescent girls and young women and expand comprehensive sexual and reproductive health care for adolescent girls and young women in rural and urban Alabama. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/44908
format Online
Article
Text
id pubmed-10131664
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher JMIR Publications
record_format MEDLINE/PubMed
spelling pubmed-101316642023-04-27 A Multicomponent Intervention to Train and Support Family Medicine Providers to Promote Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in the Deep South: Protocol for the PrEP-Pro Study Isehunwa, Oluwaseyi O Hill, Samantha V Menninger, Alex Tobias Hubner, Brook Krakower, Douglas Long, Dustin M Pratt, Madeline C Clement, Meredith E Wagoner, Nicholas Van Lanzi, Robin Gaines Simpson, Tina Elopre, Latesha Matthews, Lynn T JMIR Res Protoc Protocol BACKGROUND: Pre-exposure prophylaxis (PrEP) is a highly effective biomedical prevention intervention and a major strategy for reducing the HIV burden in the United States. However, PrEP provision and uptake remain lower than estimated needs, and in ways that may exacerbate HIV disparities among Black adolescent girls and young women in the southern United States. Data suggest that gaps in provider knowledge of HIV epidemiology and PrEP and skills assessing sexual health practices are important barriers to provision and uptake, with limited evidence-based interventions to address these gaps. OBJECTIVE: This paper describes the “PrEP-Pro” intervention, a multicomponent intervention to train and support family medicine (FM) trainees to promote PrEP for adolescent girls and young women in Alabama. METHODS: The PrEP-Pro intervention comprises 3 main components guided by the Capability-Opportunity-Motivation-Behavior (COM-B) model for behavioral change and the Consolidated Framework for Implementation Research (CFIR): (1) provider HIV epidemiology and PrEP education, (2) sexual history taking, and (3) PrEP Champions. In phase 1, we will work with community advisory boards (providers and clients) and then conduct focus groups with FM trainees to adapt content to train FM residents on HIV epidemiology and PrEP and develop implementation strategies, including provider-facing tools and client-facing educational materials. In phase 2, we will pretest and then pilot-test the initially adapted PrEP-Pro intervention with FM trainees. FM trainees will complete baseline, 3-, and 6-month questionnaires post PrEP-Pro intervention. We will also conduct in-depth interviews (IDIs) with FM pilot participants, adolescent girls and young women who accessed care after the PrEP-Pro pilot, and key stakeholders. The primary outcomes are PrEP-Pro acceptability and feasibility, which would be assessed using validated instruments at months 3 (among pretest participants) and 6 (among pilot participants). Secondary outcomes will also be assessed, including PrEP knowledge, sexual history-taking attitudes and practices, PrEP prescriptions among adolescent girls and young women encounters, and sexually transmitted infections (STIs) and HIV testing among adolescent girls and young women encounters in 6 months. RESULTS: Study results will be disseminated to practices, state health officials, and other key stakeholders to solicit feedback on implementation opportunities and challenges to inform a hybrid effectiveness implementation trial. Our results will also be presented at local and national conferences and submitted to peer-reviewed journals. CONCLUSIONS: As PrEP grows, there is a pressing need to train FM providers and develop appropriate, contextually relevant tools to support PrEP implementation. The PrEP-Pro intervention is a multicomponent intervention to train FM residents across Alabama on sexual history-taking, PrEP provision for adolescent girls and young women, and supporting practice-based PrEP Champions. The PrEP-Pro intervention is anticipated to increase PrEP prescriptions for adolescent girls and young women and expand comprehensive sexual and reproductive health care for adolescent girls and young women in rural and urban Alabama. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/44908 JMIR Publications 2023-03-21 /pmc/articles/PMC10131664/ /pubmed/36943364 http://dx.doi.org/10.2196/44908 Text en ©Oluwaseyi O Isehunwa, Samantha V Hill, Alex Tobias Menninger, Brook Hubner, Douglas Krakower, Dustin M Long, Madeline C Pratt, Meredith E Clement, Nicholas Van Wagoner, Robin Gaines Lanzi, Tina Simpson, Latesha Elopre, Lynn T Matthews. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 21.03.2023. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Research Protocols, is properly cited. The complete bibliographic information, a link to the original publication on https://www.researchprotocols.org, as well as this copyright and license information must be included.
spellingShingle Protocol
Isehunwa, Oluwaseyi O
Hill, Samantha V
Menninger, Alex Tobias
Hubner, Brook
Krakower, Douglas
Long, Dustin M
Pratt, Madeline C
Clement, Meredith E
Wagoner, Nicholas Van
Lanzi, Robin Gaines
Simpson, Tina
Elopre, Latesha
Matthews, Lynn T
A Multicomponent Intervention to Train and Support Family Medicine Providers to Promote Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in the Deep South: Protocol for the PrEP-Pro Study
title A Multicomponent Intervention to Train and Support Family Medicine Providers to Promote Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in the Deep South: Protocol for the PrEP-Pro Study
title_full A Multicomponent Intervention to Train and Support Family Medicine Providers to Promote Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in the Deep South: Protocol for the PrEP-Pro Study
title_fullStr A Multicomponent Intervention to Train and Support Family Medicine Providers to Promote Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in the Deep South: Protocol for the PrEP-Pro Study
title_full_unstemmed A Multicomponent Intervention to Train and Support Family Medicine Providers to Promote Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in the Deep South: Protocol for the PrEP-Pro Study
title_short A Multicomponent Intervention to Train and Support Family Medicine Providers to Promote Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in the Deep South: Protocol for the PrEP-Pro Study
title_sort multicomponent intervention to train and support family medicine providers to promote pre-exposure prophylaxis (prep) for adolescent girls and young women in the deep south: protocol for the prep-pro study
topic Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131664/
https://www.ncbi.nlm.nih.gov/pubmed/36943364
http://dx.doi.org/10.2196/44908
work_keys_str_mv AT isehunwaoluwaseyio amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT hillsamanthav amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT menningeralextobias amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT hubnerbrook amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT krakowerdouglas amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT longdustinm amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT prattmadelinec amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT clementmeredithe amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT wagonernicholasvan amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT lanzirobingaines amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT simpsontina amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT eloprelatesha amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT matthewslynnt amulticomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT isehunwaoluwaseyio multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT hillsamanthav multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT menningeralextobias multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT hubnerbrook multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT krakowerdouglas multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT longdustinm multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT prattmadelinec multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT clementmeredithe multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT wagonernicholasvan multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT lanzirobingaines multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT simpsontina multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT eloprelatesha multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy
AT matthewslynnt multicomponentinterventiontotrainandsupportfamilymedicineproviderstopromotepreexposureprophylaxisprepforadolescentgirlsandyoungwomeninthedeepsouthprotocolfortheprepprostudy