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Targeting the vital non-structural proteins (NSP12, NSP7, NSP8 and NSP3) from SARS-CoV-2 and inhibition of RNA polymerase by natural bioactive compound naringenin as a promising drug candidate against COVID-19
The prevalence of SARS-CoV-2-induced respiratory infections is now a major challenge worldwide. There is currently no specific antiviral drug to prevent or treat this disease. Infection with COVID-19 seriously needs to find effective therapeutic agents. In the present study, naringenin, as a potenti...
Autores principales: | Aleebrahim-Dehkordi, Elahe, Ghoshouni, Hamed, Koochaki, Pooneh, Esmaili-Dehkordi, Mohsen, Aleebrahim, Elham, Chichagi, Fatemeh, Jafari, Ali, Hanaei, Sara, Heidari-Soureshjani, Ehsan, Rezaei, Nima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131750/ https://www.ncbi.nlm.nih.gov/pubmed/37131962 http://dx.doi.org/10.1016/j.molstruc.2023.135642 |
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