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Metabolic Modulation of Intracellular Ammonia via Intravesical Instillation of Nanoporter‐Encased Hydrogel Eradicates Bladder Carcinoma

Tumor protein 53 (TP53) mutation in bladder carcinoma (BC), upregulates the transcription of carbamoyl phosphate synthetase 1 (CPS1), to reduce intracellular ammonia toxicity. To leverage ammonia combating BC, here, an intravesically perfusable nanoporter‐encased hydrogel system is reported. A biomi...

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Detalles Bibliográficos
Autores principales:	Jing, Weiqiang, Chen, Chen, Wang, Ganyu, Han, Maosen, Chen, Shouzhen, Jiang, Xin, Shi, Chongdeng, Sun, Peng, Yang, Zhenmei, Shi, Benkang, Jiang, Xinyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131795/ https://www.ncbi.nlm.nih.gov/pubmed/36775865 http://dx.doi.org/10.1002/advs.202206893

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