Lipid Nanoparticles Deliver the Therapeutic VEGFA mRNA In Vitro and In Vivo and Transform Extracellular Vesicles for Their Functional Extensions

Lipid nanoparticles (LNPs) are currently used to transport functional mRNAs, such as COVID‐19 mRNA vaccines. The delivery of angiogenic molecules, such as therapeutic VEGF‐A mRNA, to ischemic tissues for producing new blood vessels is an emerging strategy for the treatment of cardiovascular diseases...

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Detalles Bibliográficos
Autores principales: Nawaz, Muhammad, Heydarkhan‐Hagvall, Sepideh, Tangruksa, Benyapa, González‐King Garibotti, Hernán, Jing, Yujia, Maugeri, Marco, Kohl, Franziska, Hultin, Leif, Reyahi, Azadeh, Camponeschi, Alessandro, Kull, Bengt, Christoffersson, Jonas, Grimsholm, Ola, Jennbacken, Karin, Sundqvist, Martina, Wiseman, John, Bidar, Abdel Wahad, Lindfors, Lennart, Synnergren, Jane, Valadi, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131815/
https://www.ncbi.nlm.nih.gov/pubmed/36806740
http://dx.doi.org/10.1002/advs.202206187

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