Human Endonuclease ANKLE1 Localizes at the Midbody and Processes Chromatin Bridges to Prevent DNA Damage and cGAS‐STING Activation

Chromatin bridges connecting the two segregating daughter nuclei arise from chromosome fusion or unresolved interchromosomal linkage. Persistent chromatin bridges are trapped in the cleavage plane, triggering cytokinesis delay. The trapped bridges occasionally break during cytokinesis, inducing DNA...

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Detalles Bibliográficos
Autores principales: Jiang, Huadong, Kong, Nannan, Liu, Zeyuan, West, Stephen C., Chan, Ying Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131833/
https://www.ncbi.nlm.nih.gov/pubmed/36825683
http://dx.doi.org/10.1002/advs.202204388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131833/
https://www.ncbi.nlm.nih.gov/pubmed/36825683
http://dx.doi.org/10.1002/advs.202204388

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