Human RSPO1 Mutation Represses Beige Adipocyte Thermogenesis and Contributes to Diet‐Induced Adiposity (Adv. Sci. 12/2023)

Thermogenesis Inhibition of fat thermogenesis is associated with obesity. However, few mutations regulating thermogenesis are identified in obese patients. This study found that wild‐type RSPO1 is normally “cocoonized” within the extracellular matrix surrounding fibroblasts. Intriguingly, the p.R219...

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Detalles Bibliográficos
Autores principales: Sun, Yingkai, Zhang, Juan, Hong, Jie, Zhang, Zhongyun, Lu, Peng, Gao, Aibo, Ni, Mengshan, Zhang, Zhiyin, Yang, Huanjie, Shen, Juan, Lu, Jieli, Xue, Wenzhi, Lv, Qianqian, Bi, Yufang, Zeng, Yi Arial, Gu, Weiqiong, Ning, Guang, Wang, Weiqing, Liu, Ruixin, Wang, Jiqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Frontispiece
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131847/
http://dx.doi.org/10.1002/advs.202370070

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