Silk‐Gel Powered Adenoviral Vector Enables Robust Genome Editing of PD‐L1 to Augment Immunotherapy across Multiple Tumor Models

Immune checkpoint blockade based on antibodies has shown great clinical success in patients, but the transitory working manner leads to restricted therapeutic benefits. Herein, a genetically engineered adenovirus is developed as the vector to deliver CRISPR/Cas9 (sgCas9‐AdV) to achieve permanent PD‐...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Ming, Li, Hao, Zhang, Cao, Wang, Yingchao, Zhang, Cuilin, Zhang, Yuting, Zhong, Aoxue, Zhang, Da, Liu, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131848/
https://www.ncbi.nlm.nih.gov/pubmed/36840638
http://dx.doi.org/10.1002/advs.202206399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131848/
https://www.ncbi.nlm.nih.gov/pubmed/36840638
http://dx.doi.org/10.1002/advs.202206399

Ejemplares similares