Cargando…
Silk‐Gel Powered Adenoviral Vector Enables Robust Genome Editing of PD‐L1 to Augment Immunotherapy across Multiple Tumor Models
Immune checkpoint blockade based on antibodies has shown great clinical success in patients, but the transitory working manner leads to restricted therapeutic benefits. Herein, a genetically engineered adenovirus is developed as the vector to deliver CRISPR/Cas9 (sgCas9‐AdV) to achieve permanent PD‐...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131848/ https://www.ncbi.nlm.nih.gov/pubmed/36840638 http://dx.doi.org/10.1002/advs.202206399 |