Prospective cohort of COVID-19 patients requiring hospital admission in Douala, Cameroon

OBJECTIVES: To report characteristics and outcome of COVID-19 patients who required hospital admission in sub-Saharan Africa clinics with no access to invasive mechanical ventilation. METHODS: Between April and June 2021, documented COVID-19 patients with SaO(2) < 95% who were admitted in two cli...

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Detalles Bibliográficos
Autores principales: Tchamgoué, S., Ntep Eboko, M., Makamté, A., Ngagnia, A., Talla-Mba, F., Nitcheu Wendi, O., Kafando, E., Tengang, B., Sandjon, J.P., Tattevin, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10131884/
https://www.ncbi.nlm.nih.gov/pubmed/37116614
http://dx.doi.org/10.1016/j.idnow.2023.104713
Descripción
Sumario:OBJECTIVES: To report characteristics and outcome of COVID-19 patients who required hospital admission in sub-Saharan Africa clinics with no access to invasive mechanical ventilation. METHODS: Between April and June 2021, documented COVID-19 patients with SaO(2) < 95% who were admitted in two clinics in Douala (Cameroon) were invited to participate. Data were prospectively collected using a standardized questionnaire. RESULTS: We included 67 patients: 39 males (58%), median age 62 years [50–70]. Comorbidities included hypertension (n = 38, 57%), obesity (n = 26, 38%), and diabetes (n = 16, 24%). No patient reported COVID-19 vaccination. On admission, 35 patients (52%) required O(2) > 6 L/min. CT scan demonstrated extended lesions (>50%) in 50/61 cases (82%). Most patients received dexamethasone (n = 64, 96%), heparin (n = 64, 96%), chloroquine/azithromycin (n = 59, 88%), and broad-spectrum antibiotics (n = 59, 88%). Sixteen patients died (24%), after a median of 11.5 days [7.5–15.5] post-admission. CONCLUSIONS:  Despite the lack of invasive mechanical ventilation, 76% of COVID-19 patients survived.

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