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Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals
Converter gas is a large scale waste product that is usually burned to carbon dioxide and contributes to the world emission of greenhouse gases. Herein we demonstrate that instead of burning the converter gas can be used as a reducing agent in organic reactions to produce valuable pharmaceuticals an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132106/ https://www.ncbi.nlm.nih.gov/pubmed/37123198 http://dx.doi.org/10.1039/d3sc00257h |
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author | Runikhina, Sofiya A. Afanasyev, Oleg I. Kuchuk, Ekaterina A. Perekalin, Dmitry S. Jagadeesh, Rajenahally V. Beller, Matthias Chusov, Denis |
author_facet | Runikhina, Sofiya A. Afanasyev, Oleg I. Kuchuk, Ekaterina A. Perekalin, Dmitry S. Jagadeesh, Rajenahally V. Beller, Matthias Chusov, Denis |
author_sort | Runikhina, Sofiya A. |
collection | PubMed |
description | Converter gas is a large scale waste product that is usually burned to carbon dioxide and contributes to the world emission of greenhouse gases. Herein we demonstrate that instead of burning the converter gas can be used as a reducing agent in organic reactions to produce valuable pharmaceuticals and agrochemicals. In particular, amide-based selected drug molecules have been synthesized by a reaction of aromatic nitro compounds and carboxylic acids in the presence of converter gas. In addition, we showed that this gas can also be conveniently utilized to carryout classical reductive amination reaction. |
format | Online Article Text |
id | pubmed-10132106 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-101321062023-04-27 Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals Runikhina, Sofiya A. Afanasyev, Oleg I. Kuchuk, Ekaterina A. Perekalin, Dmitry S. Jagadeesh, Rajenahally V. Beller, Matthias Chusov, Denis Chem Sci Chemistry Converter gas is a large scale waste product that is usually burned to carbon dioxide and contributes to the world emission of greenhouse gases. Herein we demonstrate that instead of burning the converter gas can be used as a reducing agent in organic reactions to produce valuable pharmaceuticals and agrochemicals. In particular, amide-based selected drug molecules have been synthesized by a reaction of aromatic nitro compounds and carboxylic acids in the presence of converter gas. In addition, we showed that this gas can also be conveniently utilized to carryout classical reductive amination reaction. The Royal Society of Chemistry 2023-03-31 /pmc/articles/PMC10132106/ /pubmed/37123198 http://dx.doi.org/10.1039/d3sc00257h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Runikhina, Sofiya A. Afanasyev, Oleg I. Kuchuk, Ekaterina A. Perekalin, Dmitry S. Jagadeesh, Rajenahally V. Beller, Matthias Chusov, Denis Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals |
title | Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals |
title_full | Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals |
title_fullStr | Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals |
title_full_unstemmed | Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals |
title_short | Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals |
title_sort | catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132106/ https://www.ncbi.nlm.nih.gov/pubmed/37123198 http://dx.doi.org/10.1039/d3sc00257h |
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