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Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals

Converter gas is a large scale waste product that is usually burned to carbon dioxide and contributes to the world emission of greenhouse gases. Herein we demonstrate that instead of burning the converter gas can be used as a reducing agent in organic reactions to produce valuable pharmaceuticals an...

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Autores principales: Runikhina, Sofiya A., Afanasyev, Oleg I., Kuchuk, Ekaterina A., Perekalin, Dmitry S., Jagadeesh, Rajenahally V., Beller, Matthias, Chusov, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132106/
https://www.ncbi.nlm.nih.gov/pubmed/37123198
http://dx.doi.org/10.1039/d3sc00257h
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author Runikhina, Sofiya A.
Afanasyev, Oleg I.
Kuchuk, Ekaterina A.
Perekalin, Dmitry S.
Jagadeesh, Rajenahally V.
Beller, Matthias
Chusov, Denis
author_facet Runikhina, Sofiya A.
Afanasyev, Oleg I.
Kuchuk, Ekaterina A.
Perekalin, Dmitry S.
Jagadeesh, Rajenahally V.
Beller, Matthias
Chusov, Denis
author_sort Runikhina, Sofiya A.
collection PubMed
description Converter gas is a large scale waste product that is usually burned to carbon dioxide and contributes to the world emission of greenhouse gases. Herein we demonstrate that instead of burning the converter gas can be used as a reducing agent in organic reactions to produce valuable pharmaceuticals and agrochemicals. In particular, amide-based selected drug molecules have been synthesized by a reaction of aromatic nitro compounds and carboxylic acids in the presence of converter gas. In addition, we showed that this gas can also be conveniently utilized to carryout classical reductive amination reaction.
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spelling pubmed-101321062023-04-27 Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals Runikhina, Sofiya A. Afanasyev, Oleg I. Kuchuk, Ekaterina A. Perekalin, Dmitry S. Jagadeesh, Rajenahally V. Beller, Matthias Chusov, Denis Chem Sci Chemistry Converter gas is a large scale waste product that is usually burned to carbon dioxide and contributes to the world emission of greenhouse gases. Herein we demonstrate that instead of burning the converter gas can be used as a reducing agent in organic reactions to produce valuable pharmaceuticals and agrochemicals. In particular, amide-based selected drug molecules have been synthesized by a reaction of aromatic nitro compounds and carboxylic acids in the presence of converter gas. In addition, we showed that this gas can also be conveniently utilized to carryout classical reductive amination reaction. The Royal Society of Chemistry 2023-03-31 /pmc/articles/PMC10132106/ /pubmed/37123198 http://dx.doi.org/10.1039/d3sc00257h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Runikhina, Sofiya A.
Afanasyev, Oleg I.
Kuchuk, Ekaterina A.
Perekalin, Dmitry S.
Jagadeesh, Rajenahally V.
Beller, Matthias
Chusov, Denis
Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals
title Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals
title_full Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals
title_fullStr Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals
title_full_unstemmed Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals
title_short Catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals
title_sort catalytic utilization of converter gas – an industrial waste for the synthesis of pharmaceuticals
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132106/
https://www.ncbi.nlm.nih.gov/pubmed/37123198
http://dx.doi.org/10.1039/d3sc00257h
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