Increased clonal hematopoiesis involving DNA damage response genes in patients undergoing lung transplantation

BACKGROUND: Cellular stressors influence the development of clonal hematopoiesis (CH). We hypothesized that environmental, inflammatory, and genotoxic stresses drive the emergence of CH in lung transplant recipients. METHODS: We performed a cross-sectional cohort study of 85 lung transplant recipien...

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Detalles Bibliográficos
Autores principales: Tague, Laneshia K., Oetjen, Karolyn A., Mahadev, Anirudh, Walter, Matthew J., Anthony, Hephzibah, Kreisel, Daniel, Link, Daniel C., Gelman, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132147/
https://www.ncbi.nlm.nih.gov/pubmed/36853803
http://dx.doi.org/10.1172/jci.insight.165609

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