KIBRA upregulation increases susceptibility to podocyte injury and glomerular disease progression

Despite recent progress in the identification of mediators of podocyte injury, mechanisms underlying podocyte loss remain poorly understood, and cell-specific therapy is lacking. We previously reported that kidney and brain expressed protein (KIBRA), encoded by WWC1, promotes podocyte injury in vitr...

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Detalles Bibliográficos
Autores principales: Meliambro, Kristin, Yang, Yanfeng, de Cos, Marina, Rodriguez Ballestas, Estefania, Malkin, Caroline, Haydak, Jonathan, Lee, John R., Salem, Fadi, Mariani, Laura H., Gordon, Ronald E., Basgen, John M., Wen, Huei Hsun, Fu, Jia, Azeloglu, Evren U., He, John Cijiang, Wong, Jenny S., Campbell, Kirk N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132156/
https://www.ncbi.nlm.nih.gov/pubmed/36853804
http://dx.doi.org/10.1172/jci.insight.165002

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