Reversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer

Prostate-specific membrane antigen (PSMA) is an important cell surface target in prostate cancer. There are limited data on the heterogeneity of PSMA tissue expression in metastatic castration-resistant prostate cancer (mCRPC). Furthermore, the mechanisms regulating PSMA expression (encoded by the F...

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Detalles Bibliográficos
Autores principales: Sayar, Erolcan, Patel, Radhika A., Coleman, Ilsa M., Roudier, Martine P., Zhang, Ailin, Mustafi, Pallabi, Low, Jin-Yih, Hanratty, Brian, Ang, Lisa S., Bhatia, Vipul, Adil, Mohamed, Bakbak, Hasim, Quigley, David A., Schweizer, Michael T., Hawley, Jessica E., Kollath, Lori, True, Lawrence D., Feng, Felix Y., Bander, Neil H., Corey, Eva, Lee, John K., Morrissey, Colm, Gulati, Roman, Nelson, Peter S., Haffner, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132157/
https://www.ncbi.nlm.nih.gov/pubmed/36821396
http://dx.doi.org/10.1172/jci.insight.162907

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