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suPAR links a dysregulated immune response to tissue inflammation and sepsis-induced acute kidney injury

Acute kidney injury (AKI) secondary to sepsis results in poor outcomes and conventional kidney function indicators lack diagnostic value. Soluble urokinase plasminogen activator receptor (suPAR) is an innate immune–derived molecule implicated in inflammatory organ damage. We characterized the diagno...

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Detalles Bibliográficos
Autores principales:	Nusshag, Christian, Wei, Changli, Hahm, Eunsil, Hayek, Salim S., Li, Jing, Samelko, Beata, Rupp, Christoph, Szudarek, Roman, Speer, Claudius, Kälble, Florian, Schaier, Matthias, Uhle, Florian, Schmitt, Felix C.F., Fiedler, Mascha O., Krautkrämer, Ellen, Cao, Yanxia, Rodriguez, Ricardo, Merle, Uta, Eugen-Olsen, Jesper, Zeier, Martin, Weigand, Markus A., Morath, Christian, Brenner, Thorsten, Reiser, Jochen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132159/ https://www.ncbi.nlm.nih.gov/pubmed/37036003 http://dx.doi.org/10.1172/jci.insight.165740

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