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Unsymmetric N-heterocyclic carbene ligand enabled nickel-catalysed arylation of bulky primary and secondary amines

The arylation of sterically hindered amines represents one of the long-standing challenges in synthetic chemistry. Herein, we report a highly efficient Ni-catalysed arylation of sterically hindered primary and secondary amines with aryl chlorides or phenol derivatives enabled by an unsymmetric N-het...

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Detalles Bibliográficos
Autores principales: Wang, Zi-Chao, Li, Yan-Yu, Zhang, Shuo-Qing, Hong, Xin, Shi, Shi-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132161/
https://www.ncbi.nlm.nih.gov/pubmed/37123189
http://dx.doi.org/10.1039/d3sc00492a