A field guide to flow chemistry for synthetic organic chemists

Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious “black box” needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash...

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Detalles Bibliográficos
Autores principales: Capaldo, Luca, Wen, Zhenghui, Noël, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132167/
https://www.ncbi.nlm.nih.gov/pubmed/37123197
http://dx.doi.org/10.1039/d3sc00992k
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author Capaldo, Luca
Wen, Zhenghui
Noël, Timothy
author_facet Capaldo, Luca
Wen, Zhenghui
Noël, Timothy
author_sort Capaldo, Luca
collection PubMed
description Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious “black box” needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash unique reactivity and selectivity. By “lifting the veil” on some of the governing principles behind the observed trends, we hope that this review will serve as a useful field guide for those interested in diving into flow chemistry.
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spelling pubmed-101321672023-04-27 A field guide to flow chemistry for synthetic organic chemists Capaldo, Luca Wen, Zhenghui Noël, Timothy Chem Sci Chemistry Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious “black box” needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash unique reactivity and selectivity. By “lifting the veil” on some of the governing principles behind the observed trends, we hope that this review will serve as a useful field guide for those interested in diving into flow chemistry. The Royal Society of Chemistry 2023-03-15 /pmc/articles/PMC10132167/ /pubmed/37123197 http://dx.doi.org/10.1039/d3sc00992k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Capaldo, Luca
Wen, Zhenghui
Noël, Timothy
A field guide to flow chemistry for synthetic organic chemists
title A field guide to flow chemistry for synthetic organic chemists
title_full A field guide to flow chemistry for synthetic organic chemists
title_fullStr A field guide to flow chemistry for synthetic organic chemists
title_full_unstemmed A field guide to flow chemistry for synthetic organic chemists
title_short A field guide to flow chemistry for synthetic organic chemists
title_sort field guide to flow chemistry for synthetic organic chemists
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132167/
https://www.ncbi.nlm.nih.gov/pubmed/37123197
http://dx.doi.org/10.1039/d3sc00992k
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