Prior metabolite extraction fully preserves RNAseq quality and enables integrative multi-‘omics analysis of the liver metabolic response to viral infection

Here, we provide an in-depth analysis of the usefulness of single-sample metabolite/RNA extraction for multi-‘omics readout. Using pulverized frozen livers of mice injected with lymphocytic choriomeningitis virus (LCMV) or vehicle (Veh), we isolated RNA prior (RNA) or following metabolite extraction...

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Detalles Bibliográficos
Autores principales: Madaj, Zachary B, Dahabieh, Michael S., Kamalumpundi, Vijayvardhan, Muhire, Brejnev, Pettinga, J., Siwicki, Rebecca A., Ellis, Abigail E., Isaguirre, Christine, Escobar Galvis, Martha L., DeCamp, Lisa, Jones, Russell G., Givan, Scott A., Adams, Marie, Sheldon, Ryan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132226/
https://www.ncbi.nlm.nih.gov/pubmed/37095747
http://dx.doi.org/10.1080/15476286.2023.2204586

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