Manganese(ii) complexes stimulate antitumor immunity via aggravating DNA damage and activating the cGAS-STING pathway

Activating the cyclic GMP-AMP synthase-stimulator of the interferon gene (cGAS-STING) pathway is a promising immunotherapeutic strategy for cancer treatment. Manganese(ii) complexes MnPC and MnPVA (P = 1,10-phenanthroline, C = chlorine, and VA = valproic acid) were found to activate the cGAS-STING p...

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Detalles Bibliográficos
Autores principales: Cai, Linxiang, Wang, Ying, Chen, Yayu, Chen, Hanhua, Yang, Tao, Zhang, Shuren, Guo, Zijian, Wang, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132258/
https://www.ncbi.nlm.nih.gov/pubmed/37123182
http://dx.doi.org/10.1039/d2sc06036a

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