Advanced heart failure: from definitions to therapeutic options

Advanced heart failure (AHF) represents an ominous stage of heart failure (HF), where the expected prognosis remains poor regardless of the improvement in medical knowledge. In this review, we summarize the definition, prognosis, physiopathology, and clinical/therapeutic management of the disease, f...

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Autores principales: Garascia, Andrea, Palazzini, Matteo, Tedeschi, Andrea, Sacco, Alice, Oliva, Fabrizio, Gentile, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
PLACE 2022 Supplement Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132575/
https://www.ncbi.nlm.nih.gov/pubmed/37125285
http://dx.doi.org/10.1093/eurheartjsupp/suad028
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author Garascia, Andrea
Palazzini, Matteo
Tedeschi, Andrea
Sacco, Alice
Oliva, Fabrizio
Gentile, Piero
author_facet Garascia, Andrea
Palazzini, Matteo
Tedeschi, Andrea
Sacco, Alice
Oliva, Fabrizio
Gentile, Piero
author_sort Garascia, Andrea
collection PubMed
description Advanced heart failure (AHF) represents an ominous stage of heart failure (HF), where the expected prognosis remains poor regardless of the improvement in medical knowledge. In this review, we summarize the definition, prognosis, physiopathology, and clinical/therapeutic management of the disease, focusing on the fast and timely referral of the patient to the AHF facilities. We provide an insight of the diagnostic and therapeutic ‘work up’ performed in an Italian AHF hub, implying a deep phenotypical patients characterization in order to evaluate candidacy to the therapeutic gold standards as heart transplantation (HTx) and left ventricular assist device (LVAD).
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spelling pubmed-101325752023-04-27 Advanced heart failure: from definitions to therapeutic options Garascia, Andrea Palazzini, Matteo Tedeschi, Andrea Sacco, Alice Oliva, Fabrizio Gentile, Piero Eur Heart J Suppl PLACE 2022 Supplement Paper Advanced heart failure (AHF) represents an ominous stage of heart failure (HF), where the expected prognosis remains poor regardless of the improvement in medical knowledge. In this review, we summarize the definition, prognosis, physiopathology, and clinical/therapeutic management of the disease, focusing on the fast and timely referral of the patient to the AHF facilities. We provide an insight of the diagnostic and therapeutic ‘work up’ performed in an Italian AHF hub, implying a deep phenotypical patients characterization in order to evaluate candidacy to the therapeutic gold standards as heart transplantation (HTx) and left ventricular assist device (LVAD). Oxford University Press 2023-04-26 /pmc/articles/PMC10132575/ /pubmed/37125285 http://dx.doi.org/10.1093/eurheartjsupp/suad028 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle PLACE 2022 Supplement Paper
Garascia, Andrea
Palazzini, Matteo
Tedeschi, Andrea
Sacco, Alice
Oliva, Fabrizio
Gentile, Piero
Advanced heart failure: from definitions to therapeutic options
title Advanced heart failure: from definitions to therapeutic options
title_full Advanced heart failure: from definitions to therapeutic options
title_fullStr Advanced heart failure: from definitions to therapeutic options
title_full_unstemmed Advanced heart failure: from definitions to therapeutic options
title_short Advanced heart failure: from definitions to therapeutic options
title_sort advanced heart failure: from definitions to therapeutic options
topic PLACE 2022 Supplement Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132575/
https://www.ncbi.nlm.nih.gov/pubmed/37125285
http://dx.doi.org/10.1093/eurheartjsupp/suad028
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