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Germline stem cell integrity and quiescence are controlled by an AMPK-dependent neuronal trafficking pathway

During periods of energetic stress, Caenorhabditis elegans can execute a developmentally quiescent stage called “dauer”, during which all germline stem cells undergo a G2 cell cycle arrest. In animals that lack AMP-activated protein kinase (AMPK) signalling, the germ cells fail to arrest, undergo un...

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Detalles Bibliográficos
Autores principales: Wong, Christopher, Kadekar, Pratik, Jurczak, Elena, Roy, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132661/
https://www.ncbi.nlm.nih.gov/pubmed/37058536
http://dx.doi.org/10.1371/journal.pgen.1010716