Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity

Dysfunction of either the right or left ventricle can lead to heart failure (HF) and subsequent morbidity and mortality. We performed a genome-wide association study (GWAS) of 16 cardiac magnetic resonance (CMR) imaging measurements of biventricular function and structure. Cis-Mendelian randomizatio...

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Detalles Bibliográficos
Autores principales: Schmidt, Amand F., Bourfiss, Mimount, Alasiri, Abdulrahman, Puyol-Anton, Esther, Chopade, Sandesh, van Vugt, Marion, van der Laan, Sander W., Gross, Christian, Clarkson, Chris, Henry, Albert, Lumbers, Tom R., van der Harst, Pim, Franceschini, Nora, Bis, Joshua C., Velthuis, Birgitta K., te Riele, Anneline S. J. M., Hingorani, Aroon D., Ruijsink, Bram, Asselbergs, Folkert W., van Setten, Jessica, Finan, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132758/
https://www.ncbi.nlm.nih.gov/pubmed/37126556
http://dx.doi.org/10.1126/sciadv.add4984

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