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Coverage-preserving sparsification of overlap graphs for long-read assembly
MOTIVATION: Read-overlap-based graph data structures play a central role in computing de novo genome assembly. Most long-read assemblers use Myers’s string graph model to sparsify overlap graphs. Graph sparsification improves assembly contiguity by removing spurious and redundant connections. Howeve...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132763/ https://www.ncbi.nlm.nih.gov/pubmed/36892439 http://dx.doi.org/10.1093/bioinformatics/btad124 |