Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs

Viruses mimic host short linear motifs (SLiMs) to hijack and deregulate cellular functions. Studies of motif-mediated interactions therefore provide insight into virus-host dependencies, and reveal targets for therapeutic intervention. Here, we describe the pan-viral discovery of 1712 SLiM-based vir...

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Detalles Bibliográficos
Autores principales: Mihalič, Filip, Simonetti, Leandro, Giudice, Girolamo, Sander, Marie Rubin, Lindqvist, Richard, Peters, Marie Berit Akpiroro, Benz, Caroline, Kassa, Eszter, Badgujar, Dilip, Inturi, Raviteja, Ali, Muhammad, Krystkowiak, Izabella, Sayadi, Ahmed, Andersson, Eva, Aronsson, Hanna, Söderberg, Ola, Dobritzsch, Doreen, Petsalaki, Evangelia, Överby, Anna K., Jemth, Per, Davey, Norman E., Ivarsson, Ylva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132805/
https://www.ncbi.nlm.nih.gov/pubmed/37100772
http://dx.doi.org/10.1038/s41467-023-38015-5

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