Age-associated microenvironmental changes highlight the role of PDGF-C in ER(+) breast cancer metastatic relapse

Patients with estrogen receptor (ER)-positive breast cancer are at risk of metastatic relapse for decades after primary tumor resection and treatment, a consequence of dormant disseminated tumor cells (DTCs) reawakening at secondary sites. Here we use syngeneic ER(+) mouse models in which DTCs displ...

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Detalles Bibliográficos
Autores principales: Turrell, Frances K., Orha, Rebecca, Guppy, Naomi J., Gillespie, Andrea, Guelbert, Matthew, Starling, Chris, Haider, Syed, Isacke, Clare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132974/
https://www.ncbi.nlm.nih.gov/pubmed/36914817
http://dx.doi.org/10.1038/s43018-023-00525-y

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