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PD-L1 blockade in combination with carboplatin as immune induction in metastatic lobular breast cancer: the GELATO trial

Invasive lobular breast cancer (ILC) is the second most common histological breast cancer subtype, but ILC-specific trials are lacking. Translational research revealed an immune-related ILC subset, and in mouse ILC models, synergy between immune checkpoint blockade and platinum was observed. In the...

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Detalles Bibliográficos
Autores principales: Voorwerk, Leonie, Isaeva, Olga I., Horlings, Hugo M., Balduzzi, Sara, Chelushkin, Maksim, Bakker, Noor A. M., Champanhet, Elisa, Garner, Hannah, Sikorska, Karolina, Loo, Claudette E., Kemper, Inge, Mandjes, Ingrid A. M., de Maaker, Michiel, van Geel, Jasper J. L., Boers, Jorianne, de Boer, Maaike, Salgado, Roberto, van Dongen, Marloes G. J., Sonke, Gabe S., de Visser, Karin E., Schumacher, Ton N., Blank, Christian U., Wessels, Lodewyk F. A., Jager, Agnes, Tjan-Heijnen, Vivianne C. G., Schröder, Carolien P., Linn, Sabine C., Kok, Marleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132987/
https://www.ncbi.nlm.nih.gov/pubmed/37038006
http://dx.doi.org/10.1038/s43018-023-00542-x