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The role of radiotherapy in the updated German S2k guideline for management of Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a radiosensitive tumor and the role of radiotherapy in the management of this disease was newly defined in the recently published update of the S2k guideline on Merkel cell carcinoma of the Association of Scientific Medical Societies in Germany (AWMF). While adjuvant r...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133063/ https://www.ncbi.nlm.nih.gov/pubmed/36976298 http://dx.doi.org/10.1007/s00066-023-02068-8 |
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author | Vordermark, Dirk Höller, Ulrike |
author_facet | Vordermark, Dirk Höller, Ulrike |
author_sort | Vordermark, Dirk |
collection | PubMed |
description | Merkel cell carcinoma (MCC) is a radiosensitive tumor and the role of radiotherapy in the management of this disease was newly defined in the recently published update of the S2k guideline on Merkel cell carcinoma of the Association of Scientific Medical Societies in Germany (AWMF). While adjuvant radiotherapy of the tumor bed is broadly recommended, irradiation of the regional nodal region can be performed in patients with negative sentinel lymph nodes and high-risk factors. In patients with positive sentinel lymph nodes, it is an alternative to completion lymphadenectomy. The standard dose for adjuvant radiotherapy remains 50 Gy. |
format | Online Article Text |
id | pubmed-10133063 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-101330632023-04-28 The role of radiotherapy in the updated German S2k guideline for management of Merkel cell carcinoma Vordermark, Dirk Höller, Ulrike Strahlenther Onkol Short Communication Merkel cell carcinoma (MCC) is a radiosensitive tumor and the role of radiotherapy in the management of this disease was newly defined in the recently published update of the S2k guideline on Merkel cell carcinoma of the Association of Scientific Medical Societies in Germany (AWMF). While adjuvant radiotherapy of the tumor bed is broadly recommended, irradiation of the regional nodal region can be performed in patients with negative sentinel lymph nodes and high-risk factors. In patients with positive sentinel lymph nodes, it is an alternative to completion lymphadenectomy. The standard dose for adjuvant radiotherapy remains 50 Gy. Springer Berlin Heidelberg 2023-03-28 2023 /pmc/articles/PMC10133063/ /pubmed/36976298 http://dx.doi.org/10.1007/s00066-023-02068-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Short Communication Vordermark, Dirk Höller, Ulrike The role of radiotherapy in the updated German S2k guideline for management of Merkel cell carcinoma |
title | The role of radiotherapy in the updated German S2k guideline for management of Merkel cell carcinoma |
title_full | The role of radiotherapy in the updated German S2k guideline for management of Merkel cell carcinoma |
title_fullStr | The role of radiotherapy in the updated German S2k guideline for management of Merkel cell carcinoma |
title_full_unstemmed | The role of radiotherapy in the updated German S2k guideline for management of Merkel cell carcinoma |
title_short | The role of radiotherapy in the updated German S2k guideline for management of Merkel cell carcinoma |
title_sort | role of radiotherapy in the updated german s2k guideline for management of merkel cell carcinoma |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133063/ https://www.ncbi.nlm.nih.gov/pubmed/36976298 http://dx.doi.org/10.1007/s00066-023-02068-8 |
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